Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2064723 | 1.00 | POLB (0.37) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL4119676 | 0.98 | POLB (0.38) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Iodide SCHEMBL2464728 | 0.96 | POLB (0.37) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Bromide SCHEMBL2467102 | 0.96 | POLB (0.37) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Pyridine SCHEMBL6100271 | 0.92 | SMN1; SMN2 (0.33) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL4542337 | 0.81 | POLB (0.37) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL4446695 | 0.81 | POLB (0.34) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| SCHEMBL3276196 | 0.79 | GAA (0.38) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| SCHEMBL2868301 | 0.79 | GAA (0.38) | POLBGAAHSP90AA1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL9996099 | 0.79 | POLB (0.38) | POLBSMN1; SMN2HPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117264302-A | Styrene butadiene rubber material for inner rubber layer of wear-resistant sand-absorbing rubber tube | 蚌埠惠华管业有限公司 | 2023-12-22 | — | — | CN | claimed |
| EP-1501784-B1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-13 | — | — | EP | claimed |
| US-9651076-B2 | Dissimilar material joining structure | HYUNDAI MOTOR COMPANY (KR) | 2017-05-16 | — | — | US | claimed |
| US-20170074310-A1 | DISSIMILAR MATERIAL JOINING STRUCTURE | HYUNDAI MOTOR COMPANY (KR) | 2017-03-16 | — | — | US | claimed |
| JP-4779121-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| US-7745652-B2 | Integrated chemical processes for industrial utilization of seed oils | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-06-29 | — | — | US | claimed |
| US-20100148903-A1 | ELECTRICAL ENERGY TRANSFORMATION APPARATUS | GENERAL ELECTRIC COMPANY (US) | 2010-06-17 | — | — | US | claimed |
| US-7696398-B2 | Stabilization of olefin metathesis product mixtures | Dow GlobalTTechnologies, Inc. (US) | 2010-04-13 | — | — | US | claimed |
| US-7550607-B2 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | AUSPEX PHARMACEUTICAL, INC. (US) | 2009-06-23 | — | — | US | claimed |
| US-20090143544-A1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-06-04 | — | — | US | claimed |
| US-6235925-B1 | RING CLOSURE METHATHESIS AND NOBLE METAL CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | claimed |
| EP-1088000-A1 | POLYOLEFIN COMPOSITIONS HAVING VARIABLE TOUGHNESS AND/OR HARDNESS | Materia, Inc. (US) | 2001-04-04 | — | — | EP | claimed |
| US-6211315-B1 | USING AN UNSATURATED FATTY ESTER | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2001-04-03 | — | — | US | claimed |
| US-6166166-A | Composition and process for preparation of thermoplastic polyurethanes (TPU based on a polybutadiene soft segment) | BAYER CORPORATION (US) | 2000-12-26 | — | — | US | claimed |
| WO-2000046256-A1 | POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE | ADVANCED POLYMER TECHNOLOGIES, INC. (US) | 2000-08-10 | — | — | WO | claimed |
| EP-0990641-A1 | Process for the synthesis of alpha-substituted ring systems | Bayer Aktiengesellschaft (DE) | 2000-04-05 | — | — | EP | claimed |
| EP-0987239-A1 | Process for the preparation of alpha-substituted ringsystems | Bayer Aktiengesellschaft (DE) | 2000-03-22 | — | — | EP | claimed |
| EP-0982332-A1 | Composition and process for preparation of thermoplastic polyurethanes (tpu based on a polybutadiene soft segment) | Bayer Corporation (US) | 2000-03-01 | — | — | EP | claimed |
| WO-1999060030-A1 | POLYOLEFIN COMPOSITIONS HAVING VARIABLE TOUGHNESS AND/OR HARDNESS | MATERIA, INC. (US) | 1999-11-25 | — | — | WO | claimed |
| US-5990340-A | Polyurethane polyolefins and prepolymers based on hydroxy functional polybutadiene | BAYER CORPORATION (US) | 1999-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143544-A1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | ALOX12, SQLE, ALOX15 | POLB 642/4885GAA 1769/4885HSP90AA1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.