Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2464728 | 0.96 | POLB (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2064723 | 0.96 | POLB (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL175377 | 0.96 | POLB (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4119676 | 0.94 | POLB (0.38) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Pyridine SCHEMBL6100271 | 0.89 | SMN1; SMN2 (0.33) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL2868301 | 0.79 | GAA (0.38) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL3276196 | 0.79 | GAA (0.38) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4542347 | 0.78 | GAA (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3337845 | 0.78 | GAA (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4542337 | 0.78 | POLB (0.37) | POLBGAAHSP90AA1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501784-B1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-13 | — | — | EP | claimed |
| JP-4779121-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| US-7745652-B2 | Integrated chemical processes for industrial utilization of seed oils | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-06-29 | — | — | US | claimed |
| US-7696398-B2 | Stabilization of olefin metathesis product mixtures | Dow GlobalTTechnologies, Inc. (US) | 2010-04-13 | — | — | US | claimed |
| US-20090143544-A1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-06-04 | — | — | US | claimed |
| EP-1673328-B1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF UNSATURATED ALCOHOLS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-07-09 | — | — | EP | claimed |
| JP-2007508300-A | — | — | 2007-04-05 | — | — | JP | claimed |
| US-7176336-B2 | Preparing 9-octadecene-7,12-diol by catalyzing methyl ricinoleate derived from a seed oil, in presence of a metathesis catalyst; improved yield; use in manufacture of surfactants and thermoplastic polyurethanes | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-02-13 | — | — | US | claimed |
| US-20060167326-A1 | Stabilization of olefin metathesis product mixtures | ENERGY, UNITED STATES DEPARTMENT OF | 2006-07-27 | — | — | US | claimed |
| EP-1673328-A2 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF UNSATURATED ALCOHOLS | Dow Global Technologies Inc. (US) | 2006-06-28 | — | — | EP | claimed |
| US-20050154221-A1 | Integrate chemical processes for industrial utilization of seed oils | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2005-07-14 | — | — | US | claimed |
| WO-2005040077-A2 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF UNSATURATED ALCOHOLS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-06 | — | — | WO | claimed |
| US-20050080301-A1 | Process for the synthesis of unsaturated alcohols | DOW GLOBAL TECHNOLOGIES LLC | 2005-04-14 | — | — | US | claimed |
| EP-1501784-A1 | INTERGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093215-A1 | INTERGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-11-13 | — | — | WO | claimed |
| EP-1501784-B1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-13 | — | — | EP | disclosed |
| US-7745652-B2 | Integrated chemical processes for industrial utilization of seed oils | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20050080301-A1 | Process for the synthesis of unsaturated alcohols | DOW GLOBAL TECHNOLOGIES LLC | 2005-04-14 | — | — | US | disclosed |
| EP-1501784-A1 | INTERGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093215-A1 | INTERGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080301-A1 | Process for the synthesis of unsaturated alcohols | FASN, SQLE, ALOX12 | POLB 2524/4885GAA 3922/4885HSP90AA1 230/4885 |
| US-20060167326-A1 | Stabilization of olefin metathesis product mixtures | OSBP, IWS1, OSBP2 | POLB 438/4885GAA 3944/4885HSP90AA1 2777/4885 |
| US-20050154221-A1 | Integrate chemical processes for industrial utilization of seed oils | ALOX12, SQLE, ALOX15 | POLB 602/4885GAA 1903/4885HSP90AA1 786/4885 |
| US-20090143544-A1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | ALOX12, SQLE, ALOX15 | POLB 642/4885GAA 1769/4885HSP90AA1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.