Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.41 |
| ▸ | ITGAL | P20701 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195515 | 1.00 | ITGB2 (0.41) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6568853 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGALALDH1A1MAPT | |
| SCHEMBL6316878 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGALALDH1A1MAPT | |
| SCHEMBL6567144 | 0.83 | ITGB2 (0.49) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6310553 | 0.80 | ITGAL (0.49) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6567852 | 0.77 | ITGAL (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL6240384 | 0.76 | ALDH1A1 (0.44) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6240387 | 0.76 | ALDH1A1 (0.44) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6312354 | 0.75 | ITGAL (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6568044 | 0.75 | ITGAL (0.49) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |