Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 8/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.43 |
| ▸ | ITGAL | P20701 | 8/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316878 | 1.00 | ITGB2 (0.43) | ITGB2ICAM1ITGALPLA2G4APTGES | |
| SCHEMBL6195515 | 0.86 | ITGB2 (0.41) | ITGB2ICAM1ITGALLMNAHDAC1 | |
| SCHEMBL6568434 | 0.86 | ITGB2 (0.41) | ITGB2ICAM1ITGALLMNAHDAC1 | |
| SCHEMBL6817329 | 0.81 | ITGB2 (0.52) | ITGB2ICAM1ITGALPLA2G4APTGES | |
| SCHEMBL6568833 | 0.81 | ITGB2 (0.52) | ITGB2ICAM1ITGALPLA2G4APTGES | |
| SCHEMBL6567852 | 0.81 | ITGAL (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL6312904 | 0.80 | ITGB2 (0.52) | ITGB2ICAM1ITGAL | |
| SCHEMBL6312354 | 0.79 | ITGAL (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6568044 | 0.79 | ITGAL (0.49) | ITGB2ICAM1ITGAL | |
| SCHEMBL6312964 | 0.78 | ITGB2 (0.52) | ITGB2ICAM1ITGALHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |