Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347034 | 0.79 | EPHX2 (0.67) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL6567685 | 0.79 | EPHX2 (0.48) | ALDH1A1MAPTSMN1; SMN2HTTKMT2A | |
| SCHEMBL8602439 | 0.78 | EPHX2 (0.69) | ALDH1A1HTTKMT2AMEN1EPHX2 | |
| SCHEMBL8602435 | 0.78 | EPHX2 (0.69) | ALDH1A1HTTKMT2AMEN1EPHX2 | |
| SCHEMBL27761078 | 0.74 | EPHX2 (0.51) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL4351157 | 0.73 | EPHX2 (0.56) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL6568451 | 0.72 | KDM4E (0.69) | ALDH1A1MAPTSMN1; SMN2HTTKMT2A | |
| SCHEMBL4345924 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL8598820 | 0.71 | EPHX2 (0.70) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL8598121 | 0.71 | EPHX2 (0.70) | ALDH1A1MAPTHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |