SCHEMBL6568489

SCHEMBL6568489

Cc1[c]ccc(C2CCCCC2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.39
ACMSD Q8TDX5 2/20 0.38
BACE1 P56817 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
EPHX2 P34913 1/20 0.36
CYP11B2 P19099 1/20 0.35
MAPT P10636 3/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 2/20 0.33
HTR2C P28335 2/20 0.33
XBP1 P17861 1/20 0.33
HSP90AA1 P07900 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29125236 1.00 KMO (0.39) KMOACMSDBACE1HDAC4HDAC2
SCHEMBL11270086 0.98 HDAC4 (0.37) KMOACMSDBACE1HDAC4HDAC2
SCHEMBL27008281 0.94 ESR2 (0.35) KMOACMSDBACE1HDAC4HDAC2
SCHEMBL458962 0.92 HTR2C (0.37) HTR2C
SCHEMBL27969123 0.81
SCHEMBL19435850 0.79 SOS1 (0.34) MAPTLMNASMN1; SMN2HTR2CKMT2A
SCHEMBL1778645 0.78 KMO (0.40) KMOACMSDBACE1HDAC4HDAC2
SCHEMBL14672801 0.78 JAK2 (0.32)
SCHEMBL435127 0.77 KMO (0.39) KMOACMSDBACE1HDAC4HDAC2
SCHEMBL432693 0.77 KMO (0.39) KMOACMSDBACE1HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP claimed
CN-102844381-B Thermoplastic polymer composition and stabilizer composition SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-07-29 CN disclosed
EP-2559734-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER Sumitomo Chemical Co., Ltd (JP) 2013-02-20 EP disclosed
EP-2559736-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION Sumitomo Chemical Company Limited (JP) 2013-02-20 EP disclosed
EP-2559735-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER Sumitomo Chemical Company Limited (JP) 2013-02-20 EP disclosed
EP-2559737-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-02-20 EP disclosed
US-20130041086-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-14 US disclosed
US-20130035427-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 US disclosed
US-20130035426-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 US disclosed
US-20130032756-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 US disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed
US-5416110-A Benzyl derivatives and pesticides containing them BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed
US-5175020-A Decomposing borazoles to form boron nitride SOLVAY DEUTSCHLAND GMBH (DE) 1992-12-29 US disclosed
EP-0360085-B1 OFFSET PRINTING AND OFFSET DYESTUFFS BAYER AG (DE) 1992-12-09 EP disclosed
EP-0360085-A2 Offset printing and offset dyestuffs BAYER AG (DE) 1990-03-28 EP disclosed
EP-0028351-B1 REACTIVE DYESTUFFS AND THEIR USE IN DYEING MATERIALS CONTAINING OH OR NH BAYER AG (DE) 1984-02-22 EP disclosed
EP-0027906-B1 PROCESS FOR PREPARING SULPHON AMIDES BAYER AG (DE) 1983-05-25 EP disclosed
US-4324722-A Water-soluble substituted aminocarbonyl monoazo dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
EP-0028351-A2 Reactive dyestuffs and their use in dyeing materials containing OH or NH BAYER AG (DE) 1981-05-13 EP disclosed
EP-0027906-A1 Process for preparing sulphon amides BAYER AG (DE) 1981-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041086-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION TAF9, INTS9, PGM2 KMO 2994/4885ACMSD 747/4885BACE1 4380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.