SCHEMBL6569047

SCHEMBL6569047

O=C(O)CCC(=O)CNc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.51
ALDH1A1 P00352 4/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP2C19 P33261 1/20 0.50
FFAR4 Q5NUL3 2/20 0.46
NR4A2 P43354 1/20 0.45
ERCC1 P07992 1/20 0.44
ERCC4 Q92889 1/20 0.44
LMNA P02545 2/20 0.42
PKM P14618 1/20 0.42
KDM4E B2RXH2 1/20 0.42
AKR1C3 P42330 1/20 0.42
KEAP1 Q14145 1/20 0.42
ABAT P80404 1/20 0.42
MEN1 O00255 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27791662 0.83 ERCC1 (0.46) FFAR1ALDH1A1GAAFFAR4ERCC1
SCHEMBL23166625 0.83 L3MBTL1 (0.61) ALDH1A1L3MBTL1CYP2C19LMNAKDM4E
SCHEMBL23166009 0.82 ALDH1A1 (0.48) ALDH1A1LMNAPKMKDM4EMEN1
SCHEMBL19720271 0.81 L3MBTL1 (0.47) FFAR1ALDH1A1GAAL3MBTL1CYP2C19
SCHEMBL1330698 0.81 ABAT (0.53) FFAR1ALDH1A1GAAL3MBTL1ERCC1
Hydrochloric Acid SCHEMBL3069393 0.81 ABAT (0.53) FFAR1ALDH1A1GAAL3MBTL1ERCC1
SCHEMBL41828 0.81 ABAT (0.53) FFAR1ALDH1A1GAAL3MBTL1ERCC1
Benzene SCHEMBL27714747 0.81 ABAT (0.53) FFAR1ALDH1A1GAAL3MBTL1ERCC1
SCHEMBL7785939 0.81 ABAT (0.53) FFAR1ALDH1A1GAAL3MBTL1ERCC1
Hydrochloric Acid SCHEMBL2006870 0.81 ABAT (0.53) FFAR1ALDH1A1GAAL3MBTL1ERCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534452-B2 N-(1H-imidazol-2-yl)benzamide compound and pharmaceutical composition comprising the same as active ingredient KAINOS MEDICINE, INC. (KR) 2026-01-27 US disclosed
CN-114466844-B N- (1H-imidazol-2-yl) benzamide compound and pharmaceutical composition comprising same as active ingredient 康佳诺医疗科技发展有限公司 2025-02-18 CN disclosed
US-20220348560-A1 N-(1H-IMIDAZOL-2-YL)BENZAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT KAINOS MEDICINE, INC. (KR) 2022-11-03 US disclosed
EP-4038062-A1 N-(1H-IMIDAZOL-2-YL)BENZAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT Kainos Medicine, Inc. (KR) 2022-08-10 EP disclosed
CN-114466844-A N- (1H-imidazol-2-yl) benzamide compounds and pharmaceutical compositions containing the same as active ingredient 康佳诺医疗科技发展有限公司 2022-05-10 CN disclosed
WO-2021066559-A1 N-(1H-IMIDAZOL-2-YL)BENZAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT KAINOS MEDICINE, INC. (KR) 2021-04-08 WO disclosed
EP-1402037-A1 PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS Syngenta Participations AG (CH) 2004-03-31 EP disclosed
WO-2003000898-A1 PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS SYNGENTA PARTICIPATIONS AG (CH) 2003-01-03 WO disclosed
WO-2001082697-A2 SEED TREATMENT COMPOSITION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2001-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220348560-A1 N-(1H-IMIDAZOL-2-YL)BENZAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT IRAK4, IRAK1, IRAK2 FFAR1 312/4885ALDH1A1 1606/4885GAA 1722/4885
US-12534452-B2 N-(1H-imidazol-2-yl)benzamide compound and pharmaceutical composition comprising the same as active ingredient IRAK4, IRAK1, IRAK2 FFAR1 442/4885ALDH1A1 2758/4885GAA 2950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.