Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.66 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.66 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334264 | 0.92 | MEN1 (0.68) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL14614943 | 0.79 | MEN1 (0.59) | L3MBTL1MEN1KMT2ATDP1L3MBTL3 | |
| SCHEMBL11490502 | 0.78 | GNAI3 (0.51) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL7080193 | 0.78 | MEN1 (0.55) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL23533349 | 0.77 | GNAI3 (0.69) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL3601270 | 0.77 | GNAI3 (0.69) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL6488462 | 0.77 | GNAI3 (0.69) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL6536788 | 0.77 | GNAI3 (0.69) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8973027 | 0.77 | GNAI3 (0.69) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8973060 | 0.77 | GNAI3 (0.69) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428820-A1 | Non-imidazole alkylamines as histamine H-3-receptor ligands and their therapeutic applications | BIOPROJET (FR) | 2004-06-16 | — | — | EP | disclosed |