SCHEMBL6569134

SCHEMBL6569134

Cc1cccc(-n2c3ccccc3c3cc4c5ccccc5n(-c5cccc(C)c5)c4cc32)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.52
KDM4E B2RXH2 2/20 0.52
ATM Q13315 1/20 0.52
PMM2 O15305 1/20 0.42
MPI P34949 1/20 0.42
PHOSPHO1 Q8TCT1 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
PLA2G1B P04054 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
NOTUM Q6P988 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MGLL Q99685 1/20 0.40
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18416270 0.97 L3MBTL1 (0.58) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL2741408 0.95 L3MBTL1 (0.53) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL18416293 0.93 L3MBTL1 (0.48) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL883414 0.93 L3MBTL1 (0.59) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL17166602 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL20412014 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL17754615 0.92 L3MBTL1 (0.60) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL18381793 0.91 L3MBTL1 (0.57) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL16920068 0.90 L3MBTL1 (0.52) L3MBTL1KDM4EATMPMM2MPI
SCHEMBL12799780 0.90 L3MBTL1 (0.52) L3MBTL1KDM4EATMPMM2MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP claimed
EP-0906947-B1 Indolocarbazole electroluminescent devices XEROX CORP (US) 2003-05-21 EP claimed
US-5942340-A CHARGE TRANSPORTING COMPONENT CONTAINING INDOLOCARBAZOLE COMPOUND; ENHANCED THERMAL AND OPERATIONAL STABILITY, DURABILITY XEROX CORPORATION (US) 1999-08-24 US claimed
EP-0908787-A2 Indolocarbazole Photoconductors Xerox Corporation (US) 1999-04-14 EP claimed
EP-0906947-A1 Indolocarbazole electroluminescent devices XEROX CORPORATION (US) 1999-04-07 EP claimed
US-5843607-A Indolocarbazole photoconductors XEROX CORPORATION (US) 1998-12-01 US claimed
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP disclosed
EP-0906947-B1 Indolocarbazole electroluminescent devices XEROX CORP (US) 2003-05-21 EP disclosed
EP-0908787-A2 Indolocarbazole Photoconductors Xerox Corporation (US) 1999-04-14 EP disclosed
EP-0906947-A1 Indolocarbazole electroluminescent devices XEROX CORPORATION (US) 1999-04-07 EP disclosed
US-5843607-A Indolocarbazole photoconductors XEROX CORPORATION (US) 1998-12-01 US disclosed