SCHEMBL20412014

SCHEMBL20412014

Cc1cccc(-n2c3ccccc3c3cc4c5ccc(C)cc5n(-c5ccccc5)c4cc32)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ATM Q13315 1/20 0.53
TP53 P04637 2/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
PLA2G1B P04054 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
GAA P10253 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
POLB P06746 1/20 0.39
NOTUM Q6P988 1/20 0.38
MAT2A P31153 1/20 0.38
PMM2 O15305 1/20 0.38
MPI P34949 1/20 0.38
PHOSPHO1 Q8TCT1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18416270 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMTP53MAPT
SCHEMBL17166602 0.94 L3MBTL1 (0.53) L3MBTL1KDM4EATMTP53MAPT
SCHEMBL10206146 0.94 KDM4E (0.60) L3MBTL1KDM4EATMMAPTLMNA
SCHEMBL6569134 0.92 L3MBTL1 (0.52) L3MBTL1KDM4EATMTP53MAPT
SCHEMBL17754615 0.91 L3MBTL1 (0.60) L3MBTL1KDM4EATMTP53MAPT
SCHEMBL17691710 0.90 KDM4E (0.55) L3MBTL1KDM4EATMTP53MAPT
SCHEMBL1104947 0.89 KDM4E (0.62) L3MBTL1KDM4EATMMAPTLMNA
SCHEMBL20412009 0.89 KDM4E (0.50) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL883474 0.89 KDM4E (0.67) L3MBTL1KDM4EATMMAPTLMNA
SCHEMBL10206143 0.88 KDM4E (0.60) L3MBTL1KDM4EATMTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11765968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11765968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-20180212165-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed
US-20180212165-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212165-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, TPO, DDT L3MBTL1 541/4885KDM4E 1874/4885ATM 890/4885
US-11765968-B2 Organic electroluminescent materials and devices TPR, TPO, DDT L3MBTL1 541/4885KDM4E 1874/4885ATM 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.