Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436116 | 0.81 | CYP3A4 (0.60) | POLBKMT2ATSHRCYP3A4CYP2C19 | |
| SCHEMBL6569143 | 0.80 | TSHR (0.51) | KMT2ATSHRCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL16913114 | 0.74 | KMT2A (0.48) | POLBKMT2ATSHRCYP3A4CYP2C19 | |
| SCHEMBL12682379 | 0.73 | CYP3A4 (0.75) | POLBKMT2ATSHRCYP3A4CYP2C19 | |
| SCHEMBL16930199 | 0.72 | LMNA (0.55) | KMT2AGAAALDH1A1MAPTNPSR1 | |
| SCHEMBL30313764 | 0.72 | CTNNB1 (0.71) | KMT2ATSHRCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6600362 | 0.72 | CTNNB1 (0.71) | KMT2ATSHRCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL1493250 | 0.71 | CYP1A2 (1.00) | POLBTSHRCYP3A4CYP2C19CYP1A2 | |
| Ethylene SCHEMBL6410194 | 0.70 | TSHR (0.51) | POLBKMT2ATSHRCYP3A4CYP2C19 | |
| SCHEMBL15595487 | 0.69 | KMT2A (0.61) | POLBKMT2AALDH1A1KDM4EHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465879-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003050092-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2003-06-19 | — | — | WO | disclosed |