Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1205642 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL9959010 | 0.87 | LMNA (0.44) | APEX1LMNAEGLN1ALKBH5SUCNR1 | |
| Acrylic Acid SCHEMBL9958305 | 0.76 | LMNA (0.46) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Methacrylic Acid SCHEMBL9959129 | 0.75 | LMNA (0.37) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL285597 | 0.74 | LMNA (0.69) | APEX1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL7606415 | 0.74 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL21669246 | 0.73 | APEX1 (0.39) | APEX1LMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL1268742 | 0.72 | LMNA (0.58) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL9386508 | 0.72 | PTGS1 (0.38) | APEX1LMNA | |
| Succinic Acid SCHEMBL7784488 | 0.72 | LMNA (0.64) | APEX1LMNAEGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020045515-A1 | ADDITIVE FOR HYDRAULIC MATERIAL | 株式会社日本触媒 | 2020-03-05 | — | — | WO | disclosed |
| WO-2020045511-A1 | ADDITIVE FOR HYDRAULIC MATERIAL | 株式会社日本触媒 | 2020-03-05 | — | — | WO | disclosed |
| EP-1382657-A9 | THICKENER FOR EXCAVATING SLURRY, EXCAVATING SLURRY USING THE THICKENER, AND CAST-INPLACE UNDERGROUND PILE WORK METHOD AND UNDERGROUND CONTINUOUS WALL WORK METHOD USING THE EXCAVATING SLURRY | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20040121916-A1 | Thickener for excavating slurry, excavating slurry using the the thickener, and cast-in-place underground pile work method and underground continuius wall work method using the excavating slurry | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-06-24 | — | — | US | disclosed |