Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566283 | 0.75 | PPARG (0.46) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6407738 | 0.71 | CYP1A2 (0.45) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24456201 | 0.70 | GAA (0.48) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7281047 | 0.69 | CYP1A2 (0.46) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| Ethylene SCHEMBL6409433 | 0.69 | CYP1A2 (0.43) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL27836692 | 0.67 | CYP1A2 (0.45) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27795531 | 0.67 | CYP1A2 (0.45) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2174512 | 0.67 | GAA (0.44) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21101887 | 0.67 | GAA (0.46) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6777843 | 0.67 | LCK (0.44) | GAACYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465879-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003050092-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2003-06-19 | — | — | WO | disclosed |