Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567190 | 0.75 | LMNA (0.47) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL6569183 | 0.75 | GAA (0.40) | GAACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL6656697 | 0.75 | PPARG (0.61) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL12776310 | 0.74 | PPARG (0.53) | PPARGPPARDPPARAACHELMNA | |
| Ethylene SCHEMBL6569127 | 0.73 | LMNA (0.45) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL4818551 | 0.72 | PPARG (0.51) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL6055371 | 0.70 | PPARG (0.61) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL22420256 | 0.70 | ADRA2A (0.57) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL20676011 | 0.69 | PPARG (0.59) | PPARGPPARDPPARAACHELMNA | |
| SCHEMBL15119937 | 0.68 | PPARG (0.54) | PPARGPPARDPPARAACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465879-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2004-10-13 | — | — | EP | claimed |
| WO-2003050092-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2003-06-19 | — | — | WO | claimed |
| EP-1465879-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS GYOGYSZERGYAR RT. (HU) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003050092-A2 | PROCESS FOR THE PREPARATION OF TOFISOPAM AND NEW INTERMEDIATES | EGIS Gyógyszergyár Rt. (HU) | 2003-06-19 | — | — | WO | disclosed |