SCHEMBL6569207

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17245394	0.92	KDM4E (0.53)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL17019464	0.92	KDM4E (0.48)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL16791454	0.91	TDP1 (0.44)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL19849245	0.91	ALDH1A1 (0.43)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL20149431	0.89	POLB (0.47)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL2741409	0.88	TDP1 (0.41)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL490291	0.88	ALDH1A1 (0.50)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL29476055	0.88	ALDH1A1 (0.50)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL24356783	0.87	POLB (0.41)	TDP1CNR1CNR2GSK3AGSK3B
	SCHEMBL19769497	0.87	KDM4E (0.44)	TDP1CNR1CNR2GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.