SCHEMBL6569351

SCHEMBL6569351

Cc1ccc(-n2c3ccccc3c3ccc4c5ccccc5n(-c5ccc(C)cc5)c4c32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
MAPT P10636 2/20 0.47
HTT P42858 2/20 0.47
LMNA P02545 1/20 0.47
ALKBH5 Q6P6C2 1/20 0.43
FTO Q9C0B1 1/20 0.43
METAP2 P50579 1/20 0.41
GPR3 P46089 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
POLB P06746 1/20 0.38
LIG1 P18858 1/20 0.38
ALDH1A1 P00352 3/20 0.38
NPC1 O15118 1/20 0.38
PMM2 O15305 1/20 0.38
TP53 P04637 1/20 0.38
G6PD P11413 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15451799 0.96 KDM4E (0.59) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL18416290 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL13562928 0.89 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL18416279 0.88 L3MBTL1 (0.44) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL13562926 0.88 L3MBTL1 (0.67) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL29110 0.88 KDM4E (0.67) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL31373768 0.88 KDM4E (0.67) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL17248318 0.87 KDM4E (0.53) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL19298658 0.87 ALKBH5 (0.56) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL18416288 0.87 HPRT1 (0.44) KDM4EL3MBTL1ATMMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP claimed
EP-0908787-A2 Indolocarbazole Photoconductors Xerox Corporation (US) 1999-04-14 EP claimed
US-5843607-A Indolocarbazole photoconductors XEROX CORPORATION (US) 1998-12-01 US claimed
EP-2645444-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2018-04-25 EP disclosed
US-9343685-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-05-17 US disclosed
US-9343685-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-05-17 US disclosed
EP-2645444-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2013-10-02 EP disclosed
US-20130207097-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2013-08-15 US disclosed
US-20130207097-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2013-08-15 US disclosed
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP disclosed
EP-0908787-A2 Indolocarbazole Photoconductors Xerox Corporation (US) 1999-04-14 EP disclosed
US-5843607-A Indolocarbazole photoconductors XEROX CORPORATION (US) 1998-12-01 US disclosed