Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366571 | 0.98 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9323738 | 0.82 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL17075877 | 0.81 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL3672430 | 0.81 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11306654 | 0.78 | MAPT (0.64) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11309048 | 0.78 | MAPT (0.64) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11346165 | 0.78 | LMNA (0.58) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL27572690 | 0.78 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL121439 | 0.77 | LMNA (0.96) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL16969701 | 0.77 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191023-B1 | Method of making dihydroperimidine squaraine compounds | EASTMAN KODAK CO (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1191023-A1 | Method of making dihydroperimidine squaraine compounds | EASTMAN KODAK COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6348592-B1 | CYCLIZATION OF 1,8-DIAMINONAPHTHALENE AND 1,3-DIHYDROXYACETONE DIMER TO 2,2-DIMETHYLOLPERIMIDINE; ACYLATION; REACTION WITH SQUARIC ACID TO FORM SQUARYLIUM DYE; SALT FORMATION | EASTMAN KODAK COMPANY | 2002-02-19 | — | — | US | disclosed |
| US-5959105-A | SQUARYLIUM DYES; CATIONIC; USED AS AN INFRA RED ABSORBING DYE HAVING AN APPROPRIATE ABSORPTION MAXIMUM | FUJI PHOTO FILM CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |