Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 1-Pentanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11567428 | 0.97 | TSHR (0.77) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| Cetostearyl Alcohol SCHEMBL28381024 | 0.97 | TSHR (0.77) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| Tridecan-1-Ol SCHEMBL10889589 | 0.97 | TSHR (0.77) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| Cetyl Alcohol SCHEMBL28576067 | 0.97 | TSHR (0.77) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| 1-Hexanol SCHEMBL3474518 | 0.97 | TSHR (0.77) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| Dodecanol SCHEMBL27935969 | 0.97 | TSHR (0.77) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| Dodecanol SCHEMBL28266069 | 0.94 | TSHR (0.72) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| Octanol SCHEMBL28196238 | 0.92 | TSHR (0.68) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| 1-Pentanol SCHEMBL28860645 | 0.91 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 | |
| 1-Pentanol SCHEMBL27983494 | 0.91 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438090-B2 | Binder composition for the preparation of pigment pastes and aqueous coating compositions containing these pigment pastes | HERBERTS GESELLSCHAFTMIT BESCH (DE) | 2004-02-04 | — | — | EP | disclosed |
| EP-0581211-B1 | Aqueous coating, process for its preparation and its use in processes for multilayer coating | HERBERTS & CO GMBH (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0512523-B1 | Physically drying water-borne coatings, their preparation and their use | HERBERTS & CO GMBH (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0438090-B1 | Binder composition for the preparation of pigment pastes and aqueous coating compositions containing these pigment pastes | HERBERTS & CO GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0581211-A1 | Aqueous coating, process for its preparation and its use in processes for multilayer coating | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1994-02-02 | — | — | EP | disclosed |
| EP-0512523-A1 | Physically drying water-borne coatings, their preparation and their use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0260447-B1 | AQUEOUS COATING COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0438090-A1 | Binder composition for the preparation of pigment pastes and aqueous coating compositions containing these pigment pastes | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0260447-A2 | Aqueous coating composition, process for its preparation and its use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1988-03-23 | — | — | EP | disclosed |