Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 1-Hexanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tridecan-1-Ol SCHEMBL10889589 | 1.00 | TSHR (0.77) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Cetostearyl Alcohol SCHEMBL28381024 | 1.00 | TSHR (0.77) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL28576067 | 1.00 | TSHR (0.77) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Dodecanol SCHEMBL27935969 | 1.00 | TSHR (0.77) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Bicarbonate SCHEMBL11567428 | 1.00 | TSHR (0.77) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Dodecanol SCHEMBL28266069 | 0.97 | TSHR (0.72) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| 1-Pentanol SCHEMBL6569557 | 0.97 | SMN1; SMN2 (0.75) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Octanol SCHEMBL28196238 | 0.95 | TSHR (0.68) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| 1-Heptanol SCHEMBL25433349 | 0.92 | TSHR (0.72) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| Acetic Acid SCHEMBL9650071 | 0.92 | TSHR (0.72) | TSHRALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790286-A | ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION | 巴斯夫欧洲公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105530910-B | Oral care compositions | 加巴国际控股有限公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-106999894-A | Microcapsules | 巴斯夫欧洲公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106163492-A | The mixture of cosmetic UV absorbers | 巴斯夫欧洲公司 | 2016-11-23 | — | — | CN | disclosed |
| EP-3071625-A1 | NOVEL POLYESTER SUITABLE FOR PRODUCING CARRIER MATERIALS FOR ADHESIVE TAPES | tesa SE (DE) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015071448-A1 | NOVEL POLYESTER SUITABLE FOR PRODUCING CARRIER MATERIALS FOR ADHESIVE TAPES | TESA SE (DE) | 2015-05-21 | — | — | WO | disclosed |
| US-8586731-B2 | Hydrophobic polysaccharides with diester- or carbonate ester-containing linkages having enhanced degradation | SURMODICS, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20100316687-A1 | HYDROPHOBIC POLYSACCHARIDES WITH DIESTER- OR CARBONATE ESTER-CONTAINING LINKAGES HAVING ENHANCED DEGRADATION | SURMODICS MD, LLC | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316687-A1 | HYDROPHOBIC POLYSACCHARIDES WITH DIESTER- OR CARBONATE ESTER-CONTAINING LINKAGES HAVING ENHANCED DEGRADATION | CD44, SI, ENGASE | TSHR 3379/4885ALDH1A1 1973/4885LMNA 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.