Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 9/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760350 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL27305909 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9760198 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8024917 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL27305819 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL27306004 | 0.71 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL30973139 | 0.70 | KDM4E (0.83) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10841208 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL941508 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL6470321 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406628-A1 | TETRAHYDROQUINOLINE DERIVATIVES | Akzo Nobel N.V. (NL) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003004028-A1 | TETRAHYDROQUINOLINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2003-01-16 | — | — | WO | disclosed |