SCHEMBL941508

SCHEMBL941508

CC1=CC(C)(C)Nc2ccc(C)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
HPGD P15428 7/20 1.00
KDM4E B2RXH2 6/20 1.00
HSD17B10 Q99714 5/20 1.00
MAPT P10636 4/20 1.00
TDP1 Q9NUW8 3/20 0.67
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
L3MBTL1 Q9Y468 3/20 0.67
MAPK1 P28482 1/20 0.67
GAA P10253 1/20 0.65
PGR P06401 11/20 0.63
CYP3A4 P08684 3/20 0.61
LMNA P02545 2/20 0.61
CYP1A2 P05177 2/20 0.59
CYP2D6 P10635 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
ALOX15 P16050 1/20 0.59
ALOX12 P18054 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11447400 0.98 ALDH1A1 (0.96) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL11720246 0.92 ALDH1A1 (0.84) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL31489985 0.85 ALDH1A1 (0.73) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL941591 0.85 ALDH1A1 (0.73) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL30973139 0.83 KDM4E (0.83) ALDH1A1HPGDKDM4EHSD17B10MAPT
Hydrochloric Acid SCHEMBL2174058 0.83 ALDH1A1 (0.71) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL4175684 0.82 PGR (0.78) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL7074357 0.82 MAPT (0.69) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL4375848 0.81 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL10840490 0.81 ALDH1A1 (0.69) ALDH1A1HPGDKDM4EHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495460-B1 GREASE COMPOSITION KYODO YUSHI (JP) 2024-03-06 EP claimed
US-11162051-B2 Grease composition KYODO YUSHI CO., LTD. (JP) 2021-11-02 US claimed
US-20190177645-A1 GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2019-06-13 US claimed
EP-3495460-A1 GREASE COMPOSITION Kyodo Yushi Co., Ltd. (JP) 2019-06-12 EP claimed
EP-0694057-B1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEM CO INC (US) 2000-03-01 EP claimed
EP-0694057-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-31 EP claimed
WO-1994024235-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-27 WO claimed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US claimed
EP-3495460-B1 GREASE COMPOSITION KYODO YUSHI (JP) 2024-03-06 EP disclosed
US-11162051-B2 Grease composition KYODO YUSHI CO., LTD. (JP) 2021-11-02 US disclosed
US-20190177645-A1 GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2019-06-13 US disclosed
EP-3495460-A1 GREASE COMPOSITION Kyodo Yushi Co., Ltd. (JP) 2019-06-12 EP disclosed
CN-103194303-B Air compressor oil composition and preparation method thereof SHANGHAI HITECRUN SPECIALTY LUBRICATION TECHNOLOGY CO LTD 2014-07-09 CN disclosed
CN-103194297-B Lubricating oil composition and preparation method thereof SHANGHAI HITECRUN SPECIALTY LUBRICATION TECHNOLOGY CO LTD 2014-07-09 CN disclosed
EP-0694057-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-31 EP disclosed
WO-1994024235-A1 LUBRICANT COMPOSITION CONTAINING ANTIOXIDANT UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-10-27 WO disclosed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US disclosed
EP-0099516-A1 Process for the preparation of bis(aminocyclohexyl)dialkyl methanes BASF Aktiengesellschaft (DE) 1984-02-01 EP disclosed
US-4247664-A Polymeric alkylated 1,2 dihydroquinolines THE B. F. GOODRICH COMPANY (US) 1981-01-27 US disclosed
US-4198414-A 4-H-PYRROLO(3,2,1-IJ)QUINOLIN-1,2-DIONES A. H. ROBINS COMPANY, INC. (US) 1980-04-15 US disclosed