Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | PMM2 | O15305 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569234 | 0.95 | KDM4E (0.54) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL14454763 | 0.93 | KDM4E (0.55) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL22894292 | 0.90 | KDM4E (0.57) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL8739926 | 0.90 | KDM4E (0.57) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL15625370 | 0.88 | KDM4E (0.54) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL6570851 | 0.85 | MAPT (0.54) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL15588502 | 0.85 | FABP4 (0.42) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL17248284 | 0.84 | KDM4E (0.61) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL27864514 | 0.84 | TSPO (0.53) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL27687024 | 0.83 | CYP1A2 (0.47) | KDM4EL3MBTL1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908787-B1 | Indolocarbazole Photoconductors | XEROX CORP (US) | 2004-04-14 | — | — | EP | claimed |
| EP-0908787-A2 | Indolocarbazole Photoconductors | Xerox Corporation (US) | 1999-04-14 | — | — | EP | claimed |
| US-5843607-A | Indolocarbazole photoconductors | XEROX CORPORATION (US) | 1998-12-01 | — | — | US | claimed |
| EP-0908787-B1 | Indolocarbazole Photoconductors | XEROX CORP (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-0908787-A2 | Indolocarbazole Photoconductors | Xerox Corporation (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5843607-A | Indolocarbazole photoconductors | XEROX CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |