Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.48 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737040 | 0.75 | L3MBTL1 (0.42) | MAPTALDH1A1TDP1TSHRHPGD | |
| SCHEMBL8866097 | 0.74 | PDE7A (0.68) | PDE7APDE7BMAPTALDH1A1TDP1 | |
| SCHEMBL11557505 | 0.74 | PDE7A (0.63) | PDE7APDE7BMAPTALDH1A1TDP1 | |
| SCHEMBL9709555 | 0.73 | PDE7A (0.58) | PDE7APDE7BMAPTGSTP1GSTM2 | |
| SCHEMBL7580144 | 0.73 | MAPT (0.50) | PDE7APDE7BMAPTGSTP1GSTM2 | |
| SCHEMBL3192684 | 0.72 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL6569987 | 0.72 | MAPT (0.55) | PDE7APDE7BMAPTGSTP1GSTM2 | |
| SCHEMBL27706319 | 0.71 | HPRT1 (0.53) | ALDH1A1TDP1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL810289 | 0.71 | PDE7A (0.68) | PDE7APDE7BMAPTGSTP1GSTM2 | |
| SCHEMBL1369423 | 0.69 | CES2 (0.53) | PDE7APDE7BMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979349-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076035-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |