Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965207 | 0.83 | TAAR1 (0.53) | TAAR1SLC6A3DRD2SLC6A4FDFT1 | |
| SCHEMBL6570948 | 0.81 | HTR3E (0.49) | TAAR1NPC1IDO1 | |
| SCHEMBL25079078 | 0.80 | TAAR1 (0.53) | TAAR1SLC6A3DRD2SLC6A4HTR2B | |
| SCHEMBL6569353 | 0.79 | TSHR (0.47) | SLC6A3 | |
| SCHEMBL14671413 | 0.79 | TAAR1 (0.49) | TAAR1SLC6A3DRD2SLC6A4FDFT1 | |
| SCHEMBL11965206 | 0.78 | TAAR1 (0.52) | TAAR1SLC6A3DRD2SLC6A4IDO1 | |
| SCHEMBL27602015 | 0.77 | SLC1A1 (0.44) | TAAR1SLC6A3DRD2SLC6A4HTR2B | |
| SCHEMBL25770142 | 0.77 | TAAR1 (0.50) | TAAR1SLC6A3DRD2SLC6A4 | |
| SCHEMBL6570037 | 0.77 | TAAR1 (0.50) | TAAR1SLC6A3DRD2SLC6A4 | |
| SCHEMBL10586411 | 0.76 | TAAR1 (0.53) | TAAR1SLC6A3DRD2SLC6A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |