Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25770142 | 1.00 | TAAR1 (0.50) | TAAR1SLC6A3DRD2SLC6A4NAAA | |
| SCHEMBL11965206 | 0.98 | TAAR1 (0.52) | TAAR1SLC6A3DRD2SLC6A4SLC6A2 | |
| SCHEMBL11965207 | 0.93 | TAAR1 (0.53) | TAAR1SLC6A3DRD2SLC6A4SLC6A2 | |
| SCHEMBL5109630 | 0.85 | TAAR1 (0.57) | TAAR1SLC6A3DRD2SLC6A4SLC6A2 | |
| SCHEMBL2463637 | 0.81 | LPL (0.54) | LPLLIPG | |
| SCHEMBL12693654 | 0.80 | LPL (0.62) | TAAR1SLC6A3DRD2SLC6A4LPL | |
| SCHEMBL21453073 | 0.80 | LPL (0.62) | TAAR1SLC6A3DRD2SLC6A4LPL | |
| SCHEMBL19540034 | 0.80 | LPL (0.62) | TAAR1SLC6A3DRD2SLC6A4LPL | |
| SCHEMBL27959408 | 0.80 | TAAR1 (0.51) | TAAR1SLC6A3DRD2SLC6A4NAAA | |
| SCHEMBL3380877 | 0.79 | OPRK1 (0.62) | TAAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |