Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.45 |
| ▸ | ITGAL | P20701 | 5/20 | 0.45 |
| ▸ | LGMN | Q99538 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317517 | 1.00 | ITGB2 (0.45) | ITGB2ICAM1ITGALLGMNMAPT | |
| SCHEMBL6568425 | 0.86 | ITGB2 (0.57) | ITGB2ICAM1ITGALLGMNSMN1; SMN2 | |
| SCHEMBL6317504 | 0.82 | LGMN (0.44) | LGMNMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6567825 | 0.81 | ITGAL (0.54) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL6315913 | 0.81 | ITGAL (0.54) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL6317378 | 0.79 | ITGAL (0.59) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL6568429 | 0.79 | ITGAL (0.59) | ITGB2ICAM1ITGALTDP1 | |
| SCHEMBL6317511 | 0.79 | LGMN (0.43) | LGMNMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6308954 | 0.78 | ITGAL (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL6568662 | 0.78 | ITGAL (0.63) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |