Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 14/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 14/20 | 0.57 |
| ▸ | ITGAL | P20701 | 14/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LGMN | Q99538 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568313 | 0.88 | ITGAL (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL6570043 | 0.86 | ITGB2 (0.45) | ITGB2ICAM1ITGALKDM4ENPC1 | |
| SCHEMBL6317517 | 0.86 | ITGB2 (0.45) | ITGB2ICAM1ITGALKDM4ENPC1 | |
| SCHEMBL6567825 | 0.86 | ITGAL (0.54) | ITGB2ICAM1ITGALKDM4ENPC1 | |
| SCHEMBL6315913 | 0.86 | ITGAL (0.54) | ITGB2ICAM1ITGALKDM4ENPC1 | |
| SCHEMBL6311347 | 0.85 | ITGAL (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL6201628 | 0.83 | LGMN (0.47) | ITGB2ICAM1ITGALKDM4ESMN1; SMN2 | |
| SCHEMBL6199004 | 0.83 | ITGAL (0.77) | ITGB2ICAM1ITGALKDM4ENPC1 | |
| SCHEMBL6201623 | 0.81 | RAB9A (0.47) | ITGB2ICAM1ITGALKDM4ENPC1 | |
| SCHEMBL6568429 | 0.80 | ITGAL (0.59) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |