Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824805 | 0.91 | RXRA (0.44) | PPARGPPARAKMT2AMEN1PTGS1 | |
| SCHEMBL1822386 | 0.77 | RXRA (0.44) | KMT2AMEN1PTGS1MAPTHIF1A | |
| SCHEMBL1826922 | 0.76 | POLB (0.45) | PTGS1MAPTALDH1A1POLBHTT | |
| SCHEMBL1801707 | 0.74 | PLK1 (0.43) | KMT2AMEN1PTGS1MAPTNPC1 | |
| SCHEMBL1797326 | 0.73 | KDM4E (0.55) | KMT2AMEN1MAPTNPC1ALDH1A1 | |
| SCHEMBL1826483 | 0.71 | HPGD (0.48) | PPARGPPARAMAPTNPC1ALDH1A1 | |
| SCHEMBL6454412 | 0.70 | MAPK1 (0.52) | MAPK1CYP1A2CYP2C9 | |
| SCHEMBL5718225 | 0.70 | MAPT (0.38) | KMT2AMEN1PTGS1MAPTHIF1A | |
| SCHEMBL12258522 | 0.69 | MME (0.54) | PPARGPPARAPTGS1GAAHTT | |
| SCHEMBL12258523 | 0.69 | MME (0.54) | PPARGPPARAPTGS1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448578-A1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | Basell Polyolefine GmbH (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045964-A1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-06-05 | — | — | WO | disclosed |