Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.40 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.40 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.40 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.40 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824805 | 0.85 | RXRA (0.44) | RXRANR4A2SLC22A12KMT2APLA2G10 | |
| SCHEMBL1826483 | 0.85 | HPGD (0.48) | RXRANR4A2SLC22A12PLA2G10PLA2G2A | |
| SCHEMBL6570187 | 0.77 | PPARG (0.39) | RXRANR4A2SLC22A12KMT2APTGS1 | |
| SCHEMBL1823601 | 0.74 | FFAR1 (0.46) | RXRANR4A2SLC22A12PTGER1PTGER4 | |
| SCHEMBL23189270 | 0.71 | KMT2A (0.71) | RXRANR4A2KMT2APTGER1PTGER4 | |
| SCHEMBL3149585 | 0.71 | KMT2A (0.71) | RXRANR4A2KMT2APTGER1PTGER4 | |
| SCHEMBL2841456 | 0.71 | CYP2A6 (0.48) | CYP1A2CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL7899711 | 0.70 | OPRD1 (0.51) | PTGS2MAPTHPGDCYP2C19KDM4E | |
| SCHEMBL1826614 | 0.70 | MAPK14 (0.36) | RXRANR4A2SLC22A12MAPTAKR1C3 | |
| SCHEMBL3157543 | 0.68 | PTGER1 (0.48) | RXRANR4A2KMT2APLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854804-B1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| US-7112638-B2 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20030036612-A1 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1157027-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001047939-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-05 | — | — | WO | disclosed |