Pyridine

Pyridine

SCHEMBL6570524

NC(=O)N=S(=O)=O.c1ccncc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
F7 P08709 1/20 0.33
F3 P13726 1/20 0.33
SARM1 Q6SZW1 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT6 Q8N6T7 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
SIRT3 Q9NTG7 1/20 0.33
SIRT5 Q9NXA8 1/20 0.33
SIRT4 Q9Y6E7 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 2/20 0.30
APP P05067 1/20 0.30
GAA P10253 1/20 0.30
HCAR3 P49019 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL27713090 0.86 F7 (0.33) F7F3SARM1SIRT2SIRT6
Benzene SCHEMBL3120365 0.85 CYP3A4 (0.37) TSHRTDP1ALDH1A1GAACYP1A2
Benzene SCHEMBL27536972 0.83 CYP3A4 (0.35) TSHRTDP1ALDH1A1GAACYP1A2
Benzene SCHEMBL28203037 0.83 CYP3A4 (0.35) TSHRTDP1ALDH1A1GAACYP1A2
Pyridine SCHEMBL28095590 0.81 NAPRT (0.45) NAPRTTSHRTDP1NPC1RAB9A
SCHEMBL8661746 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7754765 0.77
Pyridine SCHEMBL1164077 0.77 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL9065525 0.77 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL1070164 0.77 NAPRT (0.60) NAPRTTSHRTDP1F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111356370-B Herbicidal composition 株式会社LG化学 2021-10-22 CN claimed
CN-111356370-A Herbicidal composition 株式会社LG化学 2020-06-30 CN claimed
WO-2020060246-A1 CONTROLLED-RELEASE AGROCHEMICAL GRANULES AND PREPARATION METHOD THEREFOR 주식회사 엘지화학 2020-03-26 WO claimed
CN-101188939-A Oil suspending agent BAYER CROPSCIENCE AG (DE) 2008-05-28 CN claimed
CN-1172931-C Herbicidally active pyridine sulfonyl urea derivatives LGCI��ʽ���� 2004-10-27 CN claimed
US-6806229-B1 SULFUR COMPOUNDS SUCH AS N-((4,6-DIMETHOXYPYRIMIDIN-2-YL) AMINOCARBONYL)-2-(2-FLUORO-1-METHOXYACTETOXY-N-PROPYL)PYRIDINE -3-SULFONAMIDE AND ISOMERS, USED AS PRE-AND/OR POST-EMERGENCE HERBICIDES LG LIFE SCIENCES (KR) 2004-10-19 US claimed
US-20040116298-A1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG LIFE SCIENCES 2004-06-17 US claimed
EP-1334099-B1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD (KR) 2004-03-10 EP claimed
EP-1334099-A1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG Chem Investment Ltd. (KR) 2003-08-13 EP claimed
EP-1334099-A4 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD (KR) 2003-08-13 EP claimed
CN-1377345-A Herbicidally active pyridine sulfonyl urea derivatives LG CI CO LTD (KR) 2002-10-30 CN claimed
WO-2002030921-A1 HERBICIDALLY ACTIVE PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD. (KR) 2002-04-18 WO claimed
EP-0639190-B1 PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD (KR) 2002-01-09 EP claimed
US-5461026-A Pyridine sulfonyl urea derivatives KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US claimed
EP-0639190-A1 PYRIDINE SULFONYL UREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-02-22 EP claimed
WO-1992014728-A1 PYRIDINE SULFONYL UREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-09-03 WO claimed
CN-115778912-B Torasemide-containing tablet and preparation method thereof 苏中药业集团股份有限公司 2024-10-01 CN disclosed
CN-117486789-A Torase Mi Gongjing salt and preparation method and application thereof 江西中医药大学 2024-02-02 CN disclosed
EP-0245058-A2 Herbicidal heterocyclic sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-11 EP disclosed
CN-87101735-A HERBICIDAL PYRIDINE SULFONAMIDES 1987-09-16 CN disclosed