Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylacetylene SCHEMBL27926128 | 0.67 | APP (0.80) | APPCYP1A2CYP1A1CYP1B1MAPT | |
| Diphenylacetylene SCHEMBL21271527 | 0.67 | APP (0.80) | APPCYP1A2CYP1A1CYP1B1MAPT | |
| SCHEMBL7597750 | 0.67 | APP (0.60) | APPCYP1A2CYP1A1CYP1B1MAPT | |
| SCHEMBL8678490 | 0.67 | APP (0.46) | APPCYP1A2MAPTCYP3A4CYP2C19 | |
| SCHEMBL7543945 | 0.66 | ALDH1A1 (0.42) | CYP1A2MAPTCYP3A4NPC1MEN1 | |
| SCHEMBL6569636 | 0.64 | ALDH1A1 (0.40) | MAPTNPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL1089399 | 0.64 | LMNA (0.43) | CYP3A4CYP2C19CYP2C9NPC1MEN1 | |
| SCHEMBL4199696 | 0.64 | ALDH1A1 (0.40) | CYP1A2MAPTCYP3A4NPC1ALDH1A1 | |
| SCHEMBL6151904 | 0.64 | ALDH1A1 (0.40) | CYP1A2MAPTCYP3A4NPC1ALDH1A1 | |
| Diphenylacetylene SCHEMBL29188592 | 0.64 | APP (1.00) | APPCYP1A2MAPTCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404446-A2 | CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS | Sasol Technology (Proprietary) Limited (ZA) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003004158-A2 | CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS | SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) | 2003-01-16 | — | — | WO | disclosed |