Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.43 |
| ▸ | CCR3 | P51677 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570411 | 0.89 | HRH1 (0.45) | HRH1CCR3KCNH2HTR2CKAT6A | |
| SCHEMBL6569275 | 0.85 | HRH1 (0.46) | HRH1CCR3KCNH2HTR2CEPHX2 | |
| SCHEMBL6570421 | 0.79 | HRH1 (0.51) | HRH1CCR3KCNH2HTR2C | |
| SCHEMBL6567411 | 0.78 | HRH1 (0.46) | HRH1CCR3KCNH2 | |
| SCHEMBL6569229 | 0.78 | HRH1 (0.47) | HRH1CCR3KCNH2SLC6A4SLC6A2 | |
| SCHEMBL6569359 | 0.73 | HRH1 (0.38) | HRH1CCR3KCNH2SLC6A4SLC6A2 | |
| SCHEMBL6569389 | 0.73 | HRH1 (0.46) | HRH1CCR3KCNH2 | |
| SCHEMBL29994691 | 0.71 | HRH1 (0.62) | HRH1KCNH2HTR2CHTR1ASLC6A4 | |
| SCHEMBL2300978 | 0.71 | HRH1 (0.62) | HRH1KCNH2HTR2CHTR1ASLC6A4 | |
| SCHEMBL6569255 | 0.70 | HRH1 (0.39) | HRH1CCR3KCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404667-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003004487-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | WO | disclosed |