Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.37 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.37 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.37 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128128 | 0.79 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL942585 | 0.79 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL6568905 | 0.78 | HRH1 (0.46) | SLC6A2SLC6A4SLC6A3P2RX7HRH1 | |
| Hydrochloric Acid SCHEMBL4107468 | 0.77 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL31381194 | 0.77 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL5468103 | 0.74 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL5461807 | 0.72 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL6569252 | 0.72 | HRH1 (0.54) | HRH1CCR3KCNH2 | |
| SCHEMBL6681927 | 0.72 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL6219350 | 0.70 | SLC6A2 (0.75) | SLC6A2SLC6A4SLC6A3ROCK1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404667-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003004487-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | WO | disclosed |