Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.63 |
| ▸ | CTSB | P07858 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333100 | 0.84 | CAPN1 (0.56) | CAPN1CTSBHDAC3HDAC6PLK4 | |
| SCHEMBL1333103 | 0.84 | CAPN1 (0.56) | CAPN1CTSBHDAC3HDAC6PLK4 | |
| SCHEMBL10414535 | 0.81 | FGF23 (0.56) | CAPN1CTSBNAPRTSMN1; SMN2TP53 | |
| SCHEMBL10414536 | 0.81 | FGF23 (0.56) | CAPN1CTSBNAPRTSMN1; SMN2TP53 | |
| SCHEMBL1905604 | 0.80 | KDM4E (0.52) | CAPN1CTSBNAPRTSMN1; SMN2KDM4E | |
| SCHEMBL1905601 | 0.80 | KDM4E (0.52) | CAPN1CTSBNAPRTSMN1; SMN2KDM4E | |
| SCHEMBL12550446 | 0.80 | CAPN1 (0.61) | CAPN1CTSBHDAC3HDAC6PLK4 | |
| SCHEMBL1335366 | 0.79 | CAPN1 (0.75) | CAPN1CTSB | |
| SCHEMBL1335172 | 0.79 | CAPN1 (0.56) | CAPN1CTSBHDAC3HDAC6MMP13 | |
| SCHEMBL1335174 | 0.79 | CAPN1 (0.56) | CAPN1CTSBHDAC3HDAC6MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073641-B1 | NEW SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2004-04-14 | — | — | EP | disclosed |