Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6569170 | 0.94 | MCHR1 (0.72) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6570867 | 0.92 | MCHR1 (0.69) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6569991 | 0.91 | MCHR1 (0.64) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6570567 | 0.91 | MCHR1 (0.72) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6570538 | 0.89 | MCHR1 (0.74) | MCHR1HTR2CSLC2A1CYP1A2POLB | |
| SCHEMBL6569846 | 0.88 | MCHR1 (0.72) | MCHR1HTR2CSLC2A1CYP1A2POLB | |
| SCHEMBL6927129 | 0.87 | MCHR1 (0.93) | MCHR1HTR2CSLC2A1CYP1A2POLB | |
| SCHEMBL6926340 | 0.87 | MCHR1 (0.92) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6572159 | 0.86 | MCHR1 (0.74) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6930451 | 0.85 | MCHR1 (0.84) | MCHR1HTR2CSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140072-B1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-04-14 | — | — | EP | disclosed |