Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.84 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6928622 | 0.90 | MCHR1 (0.67) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6926020 | 0.88 | MCHR1 (0.80) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6570567 | 0.88 | MCHR1 (0.72) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL7670306 | 0.86 | MCHR1 (0.77) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6569170 | 0.86 | MCHR1 (0.72) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6570904 | 0.85 | MCHR1 (0.71) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6926340 | 0.85 | MCHR1 (0.92) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6923388 | 0.84 | MCHR1 (0.75) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6570867 | 0.84 | MCHR1 (0.69) | MCHR1HTR2CSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL6572199 | 0.83 | MCHR1 (0.72) | MCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140072-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1140072-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040239-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-13 | — | — | WO | disclosed |