SCHEMBL6570989

SCHEMBL6570989

COc1ccccc1-c1cc(N)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
TDP1 Q9NUW8 2/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
HSD17B10 Q99714 2/20 0.46
HSP90AA1 P07900 2/20 0.45
MAPT P10636 3/20 0.45
MAPK1 P28482 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
FGB P02675 1/20 0.45
POLB P06746 1/20 0.45
THRB P10828 1/20 0.45
ADORA2A P29274 1/20 0.45
PPARG P37231 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
NCOA2 Q15596 1/20 0.45
NCOA1 Q15788 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6574711 0.98 ALDH1A1 (0.48) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
SCHEMBL6011416 0.85 ALDH1A1 (0.50) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
SCHEMBL3790445 0.85 ALDH1A1 (0.50) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
Hydrochloric Acid SCHEMBL7692397 0.83 ALDH1A1 (0.40) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
SCHEMBL19486099 0.82 BRD4 (0.47) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
SCHEMBL6572542 0.82 CA1 (0.52) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
SCHEMBL395260 0.82 ALDH1A1 (0.67) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
SCHEMBL3787198 0.81 ALDH1A1 (0.50) ALDH1A1TDP1ADRA2BPTGS1MAPT
SCHEMBL6572108 0.81 NR3C1 (0.48) ALDH1A1TDP1ADRA2BPTGS1HSD17B10
Hydrochloric Acid SCHEMBL6777773 0.81 CA1 (0.50) ALDH1A1TDP1ADRA2BPTGS1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
CN-101253222-B Polymer compound containing sulfonic acid group and organic electroluminescent element containing the same MITSUI CHEMICALS INC 2010-12-22 CN disclosed
CN-101253222-A Polymer compound containing sulfonic acid group and organic electroluminescent element containing the same MITSUI CHEMICALS INC (JP) 2008-08-27 CN disclosed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed