Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | PRKX | P51817 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741030 | 0.80 | DYRK1A (0.42) | DYRK1ANTRK1IGF1RFGFR1LTK | |
| SCHEMBL31465343 | 0.77 | DYRK1A (0.33) | DYRK1A | |
| SCHEMBL24253557 | 0.73 | GABRA1 (0.35) | DYRK1A | |
| SCHEMBL24253457 | 0.73 | GABRA1 (0.35) | DYRK1A | |
| SCHEMBL25892465 | 0.70 | PCSK9 (0.30) | — | |
| SCHEMBL15261493 | 0.69 | DYRK1A (0.40) | DYRK1ANTRK1IGF1RFGFR1LTK | |
| SCHEMBL15690267 | 0.69 | DYRK1A (0.40) | DYRK1ANTRK1IGF1RFGFR1LTK | |
| SCHEMBL1440869 | 0.67 | DYRK1A (0.49) | DYRK1AIDO1 | |
| SCHEMBL24253460 | 0.66 | PCSK9 (0.32) | DYRK1A | |
| SCHEMBL25064747 | 0.66 | PRKAB2 (0.34) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443890-A1 | OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-08-11 | — | — | EP | claimed |
| WO-2003041670-A1 | OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-05-22 | — | — | WO | claimed |
| EP-2790660-A1 | CATIONIC TETRAHYDROPYRAZOLOPYRIDINES, DYE COMPOSITION COMPRISING SUCH OXIDATION BASES, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'Oréal (FR) | 2014-10-22 | — | — | EP | disclosed |
| WO-2013087933-A1 | CATIONIC TETRAHYDROPYRAZOLOPYRIDINES, DYE COMPOSITION COMPRISING SUCH OXIDATION BASES, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |
| WO-2012080285-A2 | DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |