Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294214 | 1.00 | LMNA (0.41) | LMNAHTTSMN1; SMN2KDRSMPD1 | |
| SCHEMBL9625648 | 1.00 | LMNA (0.41) | LMNAHTTSMN1; SMN2KDRSMPD1 | |
| SCHEMBL19608592 | 1.00 | LMNA (0.41) | LMNAHTTSMN1; SMN2KDRSMPD1 | |
| SCHEMBL19159122 | 0.98 | LMNA (0.42) | LMNAHTTSMN1; SMN2KDRSMPD1 | |
| SCHEMBL299543 | 0.92 | LMNA (0.43) | LMNAHTTSMN1; SMN2KDRL3MBTL1 | |
| SCHEMBL292775 | 0.84 | — | — | |
| SCHEMBL19978685 | 0.81 | LMNA (0.41) | LMNAHTTSMN1; SMN2L3MBTL1GBA1 | |
| SCHEMBL26748843 | 0.80 | LMNA (0.36) | LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6528006 | 0.79 | ALDH1A1 (0.40) | KDRSMPD1L3MBTL1PTGS1PTGS2 | |
| SCHEMBL294213 | 0.79 | KDR (0.40) | KDRSMPD1L3MBTL1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813526-B1 | PROCESS FOR PREPARING N-SUBSTITUTED PYRAZOLES | BASF AG (DE) | 2004-02-04 | — | — | EP | disclosed |
| US-5840913-A | CATALYTIC N-ALKYLATION OF A PYRAZOLE BY REACTING WITH AN ALCOHOL; LIQUID PHASE; NON-HETEROGENOUS ACID CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |