Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572479 | 0.87 | CRHR1 (0.40) | CRHR1MAP4K4BTK | |
| SCHEMBL6574564 | 0.86 | CRHR1 (0.36) | CRHR1PDE7A | |
| SCHEMBL6572020 | 0.84 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6570914 | 0.82 | MEN1 (0.39) | — | |
| SCHEMBL6572624 | 0.82 | MAP4K4 (0.44) | CRHR1MAP4K4 | |
| SCHEMBL993884 | 0.81 | CRHR1 (0.36) | CRHR1MAP4K4 | |
| SCHEMBL6572255 | 0.81 | CRHR1 (0.38) | CRHR1MAP4K4 | |
| SCHEMBL6571975 | 0.80 | GRM2 (0.38) | CRHR1MAP4K4 | |
| SCHEMBL6571195 | 0.80 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6572090 | 0.79 | CRHR1 (0.34) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |