Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572255 | 0.89 | CRHR1 (0.38) | MAP4K4FYNCRHR1CHRM3 | |
| SCHEMBL6573087 | 0.86 | CRHR1 (0.40) | MAP4K4FYNCRHR1AOC3KMT2A | |
| SCHEMBL6571975 | 0.85 | GRM2 (0.38) | MAP4K4FYNCRHR1 | |
| SCHEMBL6571546 | 0.85 | CRHR1 (0.42) | TAAR1FYNCRHR1MAOBKMT2A | |
| SCHEMBL6572721 | 0.85 | KDM4E (0.35) | CRHR1KMT2A | |
| SCHEMBL6571312 | 0.85 | ALDH1A1 (0.44) | FYNMAOBKMT2A | |
| SCHEMBL6571031 | 0.85 | PIK3CG (0.38) | MAP4K4FYNCRHR1 | |
| SCHEMBL6571473 | 0.84 | RORB (0.42) | MAOB | |
| SCHEMBL6572058 | 0.83 | TAAR1 (0.45) | MAP4K4TAAR1FYNMAOBKMT2A | |
| SCHEMBL6572090 | 0.82 | CRHR1 (0.34) | CRHR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |