Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786764 | 0.80 | MAOB (0.70) | MAOBHTTFGFR1POLBKDM4E | |
| SCHEMBL8787412 | 0.80 | MAOB (0.54) | MAOBHTTFGFR1POLBPIK3CB | |
| SCHEMBL4583151 | 0.80 | KDM4E (0.52) | MAOBHTTFGFR1POLBKDM4E | |
| SCHEMBL8344942 | 0.78 | HTT (0.60) | MAOBHTTFGFR1POLBPIK3CB | |
| SCHEMBL5984515 | 0.74 | HTT (0.51) | HTTFGFR1POLBPIK3CBROCK1 | |
| SCHEMBL927134 | 0.73 | MAOB (0.52) | MAOBKDM4ENPC1RAB9AROCK1 | |
| SCHEMBL8787872 | 0.72 | FGFR1 (0.48) | MAOBHTTFGFR1POLBNPC1 | |
| SCHEMBL8787222 | 0.72 | MAOB (0.60) | MAOBFGFR1KDM4ENPC1RAB9A | |
| SCHEMBL17351699 | 0.70 | FGFR1 (0.62) | HTTFGFR1POLBRAB9AROCK1 | |
| SCHEMBL29602591 | 0.70 | HTT (0.55) | HTTFGFR1POLBPIK3CBROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055973-B1 | BENZIMIDAZOLES | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | claimed |
| EP-0010063-B1 | PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES | CIBA-GEIGY AG (CH) | 1982-12-29 | — | — | EP | claimed |
| US-4360679-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | claimed |
| EP-0055973-A1 | Benzimidazoles | CIBA-GEIGY AG (CH) | 1982-07-14 | — | — | EP | claimed |
| EP-0011824-B1 | BENZOFURANYL-BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OPTICAL BLEACHING OF ORGANIC MATERIALS | BAYER AG (DE) | 1981-10-14 | — | — | EP | claimed |
| US-4250317-A | OPTICAL BRIGHTENERS; FLUORESCENT DYES; TEXTILES; DETERGENTS | CIBA-GEIGY CORPORATION (US) | 1981-02-10 | — | — | US | claimed |
| EP-0011824-A1 | Benzofuranyl-benzimidazoles, process for their preparation and their use in the optical bleaching of organic materials | BAYER AG (DE) | 1980-06-11 | — | — | EP | claimed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | claimed |
| US-4146725-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | claimed |
| EP-1455352-A1 | New dyes for optical data recording | CLARIANT INTERNATIONAL LTD. (CH) | 2004-09-08 | — | — | EP | disclosed |
| EP-0864568-B1 | Agents for treatment of cardiac diseases | KUREHA CHEMICAL IND CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-4455436-A | WHITENERS | CIBA-GEIGY CORPORATION (US) | 1984-06-19 | — | — | US | disclosed |
| EP-0010063-B1 | PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES | CIBA-GEIGY AG (CH) | 1982-12-29 | — | — | EP | disclosed |
| US-4360679-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |