SCHEMBL927134

SCHEMBL927134

c1ccc2oc(-n3ccc4ccccc43)cc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.52
MAOA P21397 1/20 0.52
BIRC5 O15392 1/20 0.43
PRKD3 O94806 1/20 0.42
PRKCG P05129 1/20 0.42
PRKCB P05771 1/20 0.42
PRKCA P17252 1/20 0.42
PRKACA P17612 1/20 0.42
PRKACG P22612 1/20 0.42
PRKACB P22694 1/20 0.42
PRKCH P24723 1/20 0.42
PRKCI P41743 1/20 0.42
PRKCE Q02156 1/20 0.42
PRKCQ Q04759 1/20 0.42
PRKCZ Q05513 1/20 0.42
PRKCD Q05655 1/20 0.42
PRKD1 Q15139 1/20 0.42
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
CHRM2 P08172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571671 0.73 MAOB (0.52) MAOBKDM4ENPC1RAB9AROCK1
SCHEMBL9464614 0.73 CYP2A6 (0.42) MAOBMAOAKDM4ENPC1RAB9A
SCHEMBL11229668 0.70 BIRC5 (0.46) MAOBMAOABIRC5PRKD3PRKCG
SCHEMBL10153905 0.70 BIRC5 (0.64) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL30821446 0.69 GABRP (0.48) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL17779393 0.69 BIRC5 (0.53) MAOBMAOABIRC5PRKD3PRKCG
SCHEMBL929770 0.69 MAOB (0.37) MAOBMAOAKDM4ENPC1RAB9A
SCHEMBL27380676 0.69 GABRP (0.48) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL7777690 0.68 FLT3 (0.46) MAOBKDM4ENPC1RAB9AFLT3
SCHEMBL23890351 0.68 POLB (0.54) LOXL2CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028120-B1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use OREAL (FR) 2003-03-19 EP claimed
US-20020172647-A1 Composition containing a steroid and a liposoluble UV filter L'OREAL (FR) 2002-11-21 US claimed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 EP claimed
EP-0010063-B1 PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES CIBA-GEIGY AG (CH) 1982-12-29 EP claimed
US-20230149289-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY COVESTRO DEUTSCHLAND AG (DE) 2023-05-18 US disclosed
US-20230135505-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS COVESTRO DEUTSCHLAND AG (DE) 2023-05-04 US disclosed
EP-4125800-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS Covestro Deutschland AG (DE) 2023-02-08 EP disclosed
EP-3177267-B1 POLYURETHANEUREA SOLUTIONS FOR COSMETIC COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2022-01-05 EP disclosed
US-20210186849-A1 POLYURETHANE UREA SOLUTIONS FOR COSMETIC COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2021-06-24 US disclosed
US-20190335878-A1 FOAM OF POLYURETHANE FOR USE IN COSMETIC APPLICATIONS COVESTRO DEUTSCHLAND AG (DE) 2019-11-07 US disclosed
US-20190110977-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT L'OREAL (FR) 2019-04-18 US disclosed
US-20180303744-A1 COSMETIC COMPOSITION COMPRISING POLYURETHANE COVESTRO DEUTSCHLAND AG (DE) 2018-10-25 US disclosed
EP-1243252-A1 Skin composition containing fibres and ubiquinones L'OREAL (FR) 2002-09-25 EP disclosed
EP-1234570-A1 Cosmetic use of a matifying composition for treating greasy skin L'OREAL (FR) 2002-08-28 EP disclosed
WO-2002055046-A1 COSMETIC COMPOSITION CONTAINING MINERAL FILTERS L'OREAL (FR) 2002-07-18 WO disclosed
WO-2002043690-A1 COSMETIC COMPOSITION CONTAINING MINERAL FILTERS L'OREAL (FR) 2002-06-06 WO disclosed
EP-1203789-A1 Composition comprising a mixed silicate, polysacharide and crosslinked polymer and its utilisation L'OREAL (FR) 2002-05-08 EP disclosed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 EP disclosed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 EP disclosed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149289-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY POLR1C, CUTA, SUCLG1 MAOB 233/4885MAOA 111/4885BIRC5 2663/4885
US-20020172647-A1 Composition containing a steroid and a liposoluble UV filter SHBG, GLA, LIPA MAOB 1254/4885MAOA 605/4885BIRC5 4257/4885
US-20190110977-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT CUTA, KRT18, KIT MAOB 562/4885MAOA 1052/4885BIRC5 1369/4885
US-20180303744-A1 COSMETIC COMPOSITION COMPRISING POLYURETHANE XRCC6, PARG, PUF60 MAOB 513/4885MAOA 295/4885BIRC5 3033/4885
US-20210186849-A1 POLYURETHANE UREA SOLUTIONS FOR COSMETIC COMPOSITIONS KRT18, POLR1C, CUTA MAOB 819/4885MAOA 523/4885BIRC5 2512/4885
US-20230135505-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS UROD, PUF60, DDT MAOB 69/4885MAOA 89/4885BIRC5 3644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.