Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728401 | 0.82 | NPC1 (0.56) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL7540831 | 0.80 | CYP2C19 (0.63) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL11019441 | 0.80 | EPHX1 (0.55) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL25268462 | 0.80 | EPHX1 (0.55) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL7346371 | 0.80 | L3MBTL1 (0.62) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL9204733 | 0.77 | CYP2C19 (0.50) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| Ethylamine SCHEMBL11235220 | 0.77 | CYP2C19 (0.63) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL8001654 | 0.77 | ACE (0.53) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL10185466 | 0.77 | ALDH1A1 (0.63) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL8435170 | 0.76 | ALDH1A1 (0.58) | CYP2C19POLBALDH1A1CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140981-B1 | TRIPEPTIDE COMPOUNDS USEFUL AS SELECTIVE INHIBITORS OF AMINOPEPTIDASE A AND CORRESPONDING PHARMACEUTICAL COMPOSITIONS | INST NAT SANTE RECH MED (FR) | 2004-09-22 | — | — | EP | disclosed |
| EP-1140981-A1 | TRIPEPTIDE COMPOUNDS USEFUL AS SELECTIVE INHIBITORS OF AMINOPEPTIDASE A AND CORRESPONDING PHARMACEUTICAL COMPOSITIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000043414-A1 | TRIPEPTIDE COMPOUNDS USEFUL AS SELECTIVE INHIBITORS OF AMINOPEPTIDASE A AND CORRESPONDING PHARMACEUTICAL COMPOSITIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-07-27 | — | — | WO | disclosed |