Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571664 | 0.81 | GRIA1 (0.48) | GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL6571672 | 0.81 | KMT2A (0.48) | GRIA1GRIA2GRIA4GRIK5KMT2A | |
| SCHEMBL13992284 | 0.71 | GRIA1 (0.53) | GRIA1GRIA2GRIA4GRIK5TDP1 | |
| SCHEMBL7181578 | 0.68 | CYP1A2 (0.60) | GRIA1GRIA2GRIA4GRIK5TDP1 | |
| SCHEMBL1717207 | 0.68 | MEN1 (0.78) | GRIA1GRIA2GRIA4GRIK5KMT2A | |
| SCHEMBL125267 | 0.68 | MEN1 (0.53) | GRIA1GRIA2GRIA4GRIK5TDP1 | |
| SCHEMBL12499652 | 0.68 | MEN1 (0.57) | GRIA1GRIA2GRIA4GRIK5TDP1 | |
| SCHEMBL5117415 | 0.68 | GRIA1 (0.54) | GRIA1GRIA2GRIA4GRIK5TDP1 | |
| SCHEMBL2153060 | 0.67 | GRIA1 (0.60) | GRIA1GRIA2GRIA4GRIK5TDP1 | |
| SCHEMBL4564516 | 0.67 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884051-B1 | CANCEROUS METASTASIS INHIBITORS CONTAINING URACIL DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| EP-0763529-B1 | URACIL DERIVATIVES, AND ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6294535-B1 | TREATING CANCER, WHICH COMPRISES ADMINISTERING TO A PATIENT IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF A URACIL DERIVATIVE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| US-6255314-B1 | Cancerous metastasis inhibitors containing uracil derivatives | TAIHO CHARMACEUTICAL CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6159969-A | Uracil derivatives, and antitumor effect potentiator and antitumor agent containing the same | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0884051-A1 | CANCEROUS METASTASIS INHIBITORS CONTAINING URACIL DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5744475-A | 4-N-HET-METHYLURACIL DERIVATIVES; THYMIDINE PHOSPHORYLASE INHIBITORS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0763529-A1 | URACIL DERIVATIVES, AND ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT CONTAINING THE SAME | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1997-03-19 | — | — | EP | disclosed |