Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.54 |
| ▸ | DTYMK | P23919 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123271 | 0.88 | DTYMK (0.64) | GRIA1GRIA2GRIA4GRIK5DTYMK | |
| SCHEMBL5116514 | 0.82 | GRIA1 (0.54) | GRIA1GRIA2GRIA4GRIK5CYP2C9 | |
| SCHEMBL19103048 | 0.82 | LMNA (0.58) | GRIA1GRIA2GRIA4GRIK5CYP2C9 | |
| SCHEMBL7181578 | 0.80 | CYP1A2 (0.60) | GRIA1GRIA2GRIA4GRIK5CYP2C9 | |
| SCHEMBL19873722 | 0.80 | DTYMK (0.58) | GRIA1GRIA2GRIA4GRIK5DTYMK | |
| SCHEMBL28641604 | 0.79 | ALDH1A1 (0.48) | GRIA1GRIA2GRIA4GRIK5DTYMK | |
| SCHEMBL5125087 | 0.79 | DTYMK (0.82) | DTYMKKMT2AMEN1 | |
| SCHEMBL14208557 | 0.78 | DTYMK (0.74) | DTYMKKMT2AMEN1 | |
| SCHEMBL21695465 | 0.74 | LMNA (0.71) | GRIA1GRIA2GRIA4GRIK5DTYMK | |
| SCHEMBL21695507 | 0.72 | LMNA (0.51) | GRIA1GRIA2GRIA4GRIK5DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096907-A1 | Aryl, Pyrimidyl Compounds, Pharmaceutical Compositions Comprising them, Their Use as Antimicrobial Agents | INSTITUT PASTEUR (FR) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096907-A1 | Aryl, Pyrimidyl Compounds, Pharmaceutical Compositions Comprising them, Their Use as Antimicrobial Agents | TPMT, DHFR, TYMP | GRIA1 3530/4885GRIA2 3920/4885GRIA4 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.