Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943634 | 0.87 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL563078 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10547901 | 0.81 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10543652 | 0.81 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2228926 | 0.80 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5272875 | 0.79 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10729261 | 0.79 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| Acetic Acid SCHEMBL6571740 | 0.78 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9788130 | 0.78 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10726283 | 0.78 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752612-B1 | Electrochromic device | NIPPON MITSUBISHI OIL CORP (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-5859722-A | Electrochromic device | NIPPOM OIL CO., LTD (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0752612-A1 | Electrochromic device | NIPPON OIL CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-4812575-A | ULTRAVIOLET RADIATION ABSORBER | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1989-03-14 | — | — | US | disclosed |