Toluic Acid

Toluic Acid

SCHEMBL148201

Cc1ccccc1C(=O)O.Cc1ccccc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
ALOX15 P16050 1/20 0.65
HPGD P15428 4/20 0.64
KDM4E B2RXH2 3/20 0.64
HSD17B10 Q99714 2/20 0.64
MYC P01106 2/20 0.63
CYP3A4 P08684 2/20 0.59
CYP2C9 P11712 2/20 0.59
KMT2A Q03164 2/20 0.59
POLB P06746 1/20 0.57
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
NAPRT Q6XQN6 2/20 0.55
AKR1C3 P42330 2/20 0.55
MEN1 O00255 1/20 0.55
AKR1B10 O60218 1/20 0.55
TRPA1 O75762 1/20 0.55
ABCB11 O95342 1/20 0.55
DHFR P00374 1/20 0.55
LMNA P02545 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluic Acid SCHEMBL4152 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL28037745 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6571818 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL29414127 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL5748070 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6913552 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6913659 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL4730975 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6915532 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6113300 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870620-B Lubricant composition 国际壳牌研究有限公司 2017-11-24 CN disclosed
US-20120058024-A1 SYSTEM AND PROCESS FOR PRODUCTION OF BENZOIC ACIDS AND PHTHALIC ACIDS H R D CORPORATION (US) 2012-03-08 US disclosed
US-7994330-B2 Oxidizing p-xylene to terephthalic acid using a catalyst having a dicarboximide skeleton; hydrothermally treating the product with hot water, decomposing and removing catalyst impurities DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-09 US disclosed
WO-2011031424-A2 HIGH SHEAR SYSTEM AND METHOD FOR THE PRODUCTION OF ACIDS HRD CORPORATION (US) 2011-03-17 WO disclosed
US-20110031000-A1 RESIN COMPOSITION, CARRIER MATERIAL WITH RESIN, MULTI-LAYERED PRINTED CIRCUIT BOARD, AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2011-02-10 US disclosed
US-20090092975-A1 SELECTABLE MARKER MOLOGIC LTD (GB) 2009-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092975-A1 SELECTABLE MARKER AMD1, PADI1, PSAT1 ALDH1A1 46/4885ALOX15 2628/4885HPGD 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.