SCHEMBL6571848

SCHEMBL6571848

CCC(F)([SiH3])C(=O)N(F)F

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4018065 0.76
SCHEMBL6708241 0.75 FAAH (0.34) FAAHCES1CES2MEN1CYP1A2
SCHEMBL6653507 0.72
SCHEMBL10596442 0.71
SCHEMBL4000795 0.66
SCHEMBL21580899 0.66
SCHEMBL2804056 0.64
SCHEMBL3618069 0.60
SCHEMBL50593 0.60
SCHEMBL13104142 0.60 ALDH1A1 (0.32) FAAHCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404701-A1 METHOD FOR PREPARING OESTROGEN DERIVATIVES Aventis Pharma S.A. (FR) 2004-04-07 EP disclosed
WO-2002100880-A1 METHOD FOR PREPARING OESTROGEN DERIVATIVES AVENTIS PHARMA S.A. (FR) 2002-12-19 WO disclosed
EP-0531325-A4 LOW SATURATE FRYING OIL WITH FRIED FLAVOR 1993-04-21 EP disclosed
EP-0531325-A1 LOW SATURATE FRYING OIL WITH FRIED FLAVOR. PROCTER & GAMBLE (US) 1993-03-17 EP disclosed
EP-0465494-A1 PROCESS FOR FERMENTATIVE PRODUCTION OF 2-(4-HYDROXYPHENOXY-)PROPIONIC ACID. BASF AG (DE) 1992-01-15 EP disclosed
WO-1991017666-A1 LOW SATURATE FRYING OIL WITH FRIED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 1991-11-28 WO disclosed
WO-1990011362-A1 PROCESS FOR FERMENTATIVE PRODUCTION OF 2-(4-HYDROXYPHENOXY-)PROPIONIC ACID BASF AKTIENGESELLSCHAFT (DE) 1990-10-04 WO disclosed