Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.47 |
| ▸ | F7 | P08709 | 11/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.47 |
| ▸ | F3 | P13726 | 10/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.47 |
| ▸ | F2 | P00734 | 17/20 | 0.42 |
| ▸ | PLAU | P00749 | 7/20 | 0.39 |
| ▸ | PLAT | P00750 | 7/20 | 0.39 |
| ▸ | PLG | P00747 | 4/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573952 | 0.84 | MMP2 (0.37) | PRSS1 | |
| SCHEMBL5883124 | 0.73 | F7 (0.55) | F10F7PRSS1F3PRSS2 | |
| SCHEMBL6563528 | 0.72 | PRSS1 (0.51) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL5882728 | 0.71 | F7 (0.58) | F10F7PRSS1F3PRSS2 | |
| SCHEMBL6561829 | 0.71 | F2 (0.40) | F10F7PRSS1F3PRSS2 | |
| SCHEMBL6571927 | 0.71 | ALDH1A1 (0.47) | F10F7F2PLAUPLAT | |
| Acetic Acid SCHEMBL5882781 | 0.71 | F7 (0.53) | F10F7PRSS1F3PRSS2 | |
| Hydrochloric Acid SCHEMBL5882742 | 0.71 | F7 (0.57) | F10F7PRSS1F3PRSS2 | |
| SCHEMBL5882364 | 0.70 | F7 (0.51) | F10F7PRSS1F3PRSS2 | |
| SCHEMBL5882786 | 0.70 | F7 (0.44) | F10F7PRSS1F3PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414790-A1 | SUBSTITUTED N-ACYL ANILINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003000653-A1 | SUBSTITUTED N-ACYL ANILINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG (DE) | 2003-01-03 | — | — | WO | disclosed |